Research in the lab


The main research interest of the lab is measuring brain micro-structure with magnetic resonance imaging (MRI). The general work hypothesis is that brain structure, function and behavior are linked. Under this hypothesis we study the anatomical characteristics of brain tissue as well as structural aspects of neuro-plasticity and behavioral correlates.

The research in the lab focuses on magnetic resonance imaging (MRI) in humans and rodents. We use a General Electric ® 3T scanner (located at Tel Aviv Sourasky Medical Center) for humans and a Bruker ® 7T scanner for small animals located at Tel Aviv University Campus. With these facilities we investigate brain macro-anatomy, micro-strucutre and plasticity.

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Selected Publications


Assaf Y, Pasternak O., Diffusion tensor imaging (DTI)-based white matter mapping in brain research: a review. J Mol Neurosci 2008;34(1):51-61.

Assaf Y, Blumenfeld-Katzir T, Yovel Y, Basser PJ. AxCaliber: a method for measuring axon diameter distribution from diffusion MRI. Magn Reson Med 2008;59(6):1347-1354.

Barazany D, Basser PJ, Assaf Y. In vivo measurement of axon diameter distribution in the corpus callosum of rat brain. Brain 2009;132(Pt 5):1210-1220.

Blumenfeld-Katzir T, Pasternak O, Dagan M, Assaf Y., Diffusion MRI of structural brain plasticity induced by a learning and memory task. PLoS One 2011;6(6):e20678
Sasson E, Doniger GM, Pasternak O, Tarrasch R, Assaf Y., Structural correlates of cognitive domains in normal aging with diffusion tensor imaging. Brain Struct Funct 2012;217(2):503-515
Sagi Y, Tavor I, Hofstetter S, Tzur Moryosef S, Blumenfeld-Katzir T, Assaf Y., Learning in the fast lane: New insights into neuroplasticity. Neuron 2012; 73(6), 1195-1203
Assaf Y, Alexander DC, Jones DK, Bizzi A, Behrens TE, Clark CA, Cohen Y, Dyrby TB, Huppi PS, Knoesche TR, Le-Bihan D, Parker GJ., The CONNECT project: Combining macro- and micro-structure., Neuroimage 2013
Hofstetter S, Tavor I, Tzur Moryosef S, Assaf Y., Short-term learning induces white matter plasticity in the fornix., J Neuroscience. 2013 Jul 31;33(31):12844-50

Horowitz A, Barazany D, Tavor I, Bernstein M, Yovel G, Assaf Y. , In vivo correlation between axon diameter and conduction velocity in the human brain. Brain Struct Funct. 2014 Aug 20

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Contact Us

Our lab is located at Sherman building, room #421. This building is part of the George S. Wise faculty of life-sciences, Tel Aviv University

Address: Sherman Bldg, room #421

Tel. (Yaniv):+972-3-6407661

Tel. (Lab):+972-3-6406980


E-mail: assafyan -at-